Search results for "double-blind placebo-controlled"

showing 4 items of 4 documents

Monosodium benzoate hypersensitivity in subjects with persistent rhinitis

2004

Background:  Very few data are available from the literature on whether nonatopic subjects affected by persistent rhinitis may show the appearance of objective symptoms of rhinitis after the ingestion of food additives such as tartrazine (E102), erythrosine (E127), monosodium benzoate (E211), p-hydroxybenzoate (E218), sodium metabisulphite (E223), and monosodium glutamate (E620). It is still unclear whether the ingestion of food additive may cause, as well, a consensual reduction of nasal peak inspiratory flow (NPIFR). Therefore, we used a double-blind placebo-controlled (DBPC) study to evaluate this hypothesis. Patients and methods:  Two hundred and twenty-six consecutive patients (76 male…

AdultHypersensitivity ImmediateMaleAllergymedicine.medical_specialtySettore MED/09 - Medicina InternaAdolescentMonosodium glutamateImmunologyGastroenterologychemistry.chemical_compoundVasomotor RhinitisInternal medicineImmunopathologySodium BenzoatemedicineImmunology and AllergyIngestionHumansMonosodium benzoate; hypersensitivity; persistent rhinitisChildRhinitisbusiness.industryMonosodium benzoatedouble-blind placebo-controlledMiddle Agednasal peak inspiratory flowmedicine.diseasefood additivesRegimenchemistryImmunologyChronic DiseaseEtiologyFood PreservativesFemalehypersensitivityNasal CavitybusinessPulmonary Ventilationpersistent rhinitisTartrazine
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Abdominal Ultrasound Does Not Reveal Significant Alterations in Patients With Nonceliac Wheat Sensitivity

2017

Abstract GOALS: The goal of this study was (A) to evaluate abdominal ultrasound signs in nonceliac wheat sensitivity (NCWS) patients for features useful in diagnosis and (B) to compare these aspects with those of celiac patients to assess whether ultrasound can be useful in the differential diagnosis between NCWS and celiac disease (CD). BACKGROUND: NCWS diagnosis is difficult as no biomarkers of this condition have as yet been identified. In CD ultrasound aspects have been identified that have a good diagnostic accuracy. STUDY: We prospectively recruited 45 NCWS patients (11 males, 34 females; mean age 35.7 y). Three control groups were included: (A) 99 age-matched CD patients; (B) 18 pati…

AdultMalemedicine.medical_specialtyNon-Celiac Wheat sensitivity Celiac Disease Abdominal Ultrasound Seronegative celiac disease Double-blind placebo-controlled challengeSettore MED/09 - Medicina InternaGlutensWheat HypersensitivityGastroenterology030218 nuclear medicine & medical imagingDiagnosis DifferentialIrritable Bowel SyndromeDiet Gluten-FreeYoung Adult03 medical and health sciences0302 clinical medicineDouble-Blind MethodInternal medicineElimination dietAbdomenAscitesmedicineHumansMesenteric lymph nodesProspective StudiesProspective cohort studyIrritable bowel syndromeUltrasonographybusiness.industryUltrasoundGastroenterologyMiddle Agedmedicine.diseaseCeliac Diseasemedicine.anatomical_structureFemale030211 gastroenterology & hepatologyGluten freemedicine.symptomDifferential diagnosisbusiness
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Diagnosis of Non-Celiac Gluten Sensitivity (NCGS): The Salerno Experts’ Criteria

2015

Non-Celiac Gluten Sensitivity (NCGS) is a syndrome characterized by intestinal and extra-intestinal symptoms related to the ingestion of gluten-containing food, in subjects that are not affected by either celiac disease or wheat allergy. Given the lack of a NCGS biomarker, there is the need for standardizing the procedure leading to the diagnosis confirmation. In this paper we report experts' recommendations on how the diagnostic protocol should be performed for the confirmation of NCGS. A full diagnostic procedure should assess the clinical response to the gluten-free diet (GFD) and measure the effect of a gluten challenge after a period of treatment with the GFD. The clinical evaluation i…

Diagnosis; Non-Celiac Gluten SensitivityPediatricsmedicine.medical_specialtySettore MED/09 - Medicina InternaGlutensdiagnosislcsh:TX341-641DiseasePlaceboArticleDiet Gluten-FreeDouble-Blind MethodRating scaleSurveys and QuestionnairesHumansMedicineIntestinal MucosaIrritable bowel syndromedouble-blind placebo-controlled challengechemistry.chemical_classificationirritable bowel syndromeCross-Over StudiesNutrition and Dieteticsbusiness.industrynon-celiac gluten sensitivitygastrointestinal symptom rating scalenutritional and metabolic diseasesmedicine.diseaseGlutenCrossover studySurgerychemistryImmunoglobulin GBiomarker (medicine)businesslcsh:Nutrition. Foods and food supplyBiomarkersFood HypersensitivityWheat allergyFood ScienceDiagnosiNutrients
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Non-Celiac Wheat Sensitivity Diagnosed by Double-Blind Placebo-Controlled Challenge: Exploring a New Clinical Entity.

2012

Non-Celiac Wheat Sensitivity Diagnosed by Double-Blind Placebo-Controlled Challenge: Exploring a New Clinical Entity

Non-Celiac Wheat SensitivityPediatricsmedicine.medical_specialtySettore MED/09 - Medicina InternaHepatologybusiness.industryNon-celiac gluten sensitivityGastroenterologyDouble-Blind Placebo-Controlled Challengenutritional and metabolic diseasesfood and beveragesmedicine.diseasePlaceboFood hypersensitivitydigestive system diseasesDouble blindNon-Celiac Wheat Sensitivity; Double-Blind Placebo-Controlled Challenge;Severity of illnessmedicineDifferential diagnosisbusinessNon-celiac gluten sensitivityIrritable bowel syndromeWheat allergy
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